Do we think in the two studies the growth factor induced signal transduction derived modification of alternative variants in early time points scale? Need your all views.
Many alternative splice variants such as of Caspase 9, MAX, MCL1 having anti apoptotic role, however Over expression of any of these alternative variants bypassing Or inducing resistance is sparsely understood.
Control on occurrence on alternative splice variants can be done by designing drug against deregulated splice factors.
We are working toward to understand the biology of splice factor in cancer cells, to restrict the path of origination of splice variants.
Any more ideas are welcome!!
Splice variants of apoptotic genes such as of caspase9, MCL1, MAX etc. have anti apoptotic role.
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