Does anyone have experience with Flutamide + Abireterone + prednisone (without analog LHRH) for prostate cancer resistant to castration?

More Diego Barreiro's questions See All

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Hello fellow researcher .. What is the meaning of your name?

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No title

Does anyone have the experience of using Taq Man probes in the QIAGEN Rotar- Gene qPCR machine?

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Javier Cassinello Espinosa

I do not have experience on that. But nowadays is ongoing a trial with abiraterone plus enzalutamide ( but with analog LHRH) a more active antiandrogen.

Diego Barreiro

I have 5 patients with abiratetone and prednisone withouth analog LHRH and with cartration levels of testosterone. I readt that flutamide could improve the results of abiraterona.

Ian D Davis

This is not a very logical approach. Rebound elevation of androgens occurs within a few days after abiraterone monotherapy due to high gonadotrophin levels, so your flutamide will be trying to block physiological or supraphysiological androgen levels before very long.

http://www.ncbi.nlm.nih.gov/pubmed/15150570