Hi there,
I recently purchased Apex Safe DNA Stain from Genesee for DNA gel electrophoresis, and made the switch from GelRed (Biotium), just for ease of ordering/price.
While the suppliers documents suggest it should be as good as EtBr, I seem to be having issues not only with visualization (super faint bands at recommended 5 ul per 100 ml), but with migration of DNA after restriction digest (plasmids I know should and have previously digested fine appear not to). I've even tried adding it to running buffer with no joy.
Has anyone else used this product and had similar issues? Debating whether to send it back and go back to the trusted GelRed, or if I am missing a trick.
Thanks!