It is possible that it was happened. There are processes which indicate re assortment, as genes of body color are expressed due to change in the environment, they appear only due to switch on gene activity. when temperature and ecological factors they again become normal a silent copy of gene which can not be traced by molecular methods appear. As use of drug making the insects and micro-organisms resistant only due to exposure. If exposure is not provided then they come back to their normal position. Alienation and de-alienation always happen with the chance and frequency of mutations in important genes which are highly susceptible to environmental changes.