I guess it does affect the kind of question the researcher will ask. In case of appreciative inquiry, the researcher would empathize with the interviewee.
That's what paradigm is about... according to Kuhn, we are linked to the certain way of thinking, reasoning, See also D. North, eg....
when we belong to a certain circle, we share our beliefs, upon which we construct "shared mental models", then build ideologies, methods of reasoning etc...
well, as human beings we belong to different circles at the same time, so we can try to tame our attitudes and beliefs by applying various scientific methods with control factors, but I personally think that it does not make the whole process of scientific exploration completely free from a certain paradigm...
There`s no necessary to take a particular paradigm, but we must respect the cultural and social conduct candidate aspects, and or methodology aspects. See ( Wahyuni 2014; Wolgemuth et. al. 2014; Kyambi et. al. 2014; Melchers, Ingold, Whilhelmy, Kleinmman, 2014), you must be pragmatic and innovative, may be. I hope had been useful. Greetings.
Entering an interview with a certain paradigm may affect your approach to others. You can make notes later and ask colleagues to judge if you are biased in your interaction with the people you are interviewing. None of us is completely objective. Mary V. Donohue