There is a very suitable Jacobi formula for a derivative of the determinant, which works, in particular, for the singular matrices, det' A = trace [A* Inverse (A)], were A* is the adjugate matrix.
Does a similar formula for the second derivatives of the determinant exist, working, in particular, for the singular matrices? The derivative of the adjugate matrix is A* is unknown, while the derivatives and second derivative of each component of the source matrix A are known