Has there ever been documented cross reactivity between antibodies to Plasmodium vivax AMA-1 or MSP-1 antigens and other malaria parasites or other pathogens in peer reviewed literature?
I can not remember specifically for AMA-1 or MSP1. I remember one work of Dr. Mutapi investigating cross reactivity between MSP3 and GLURP with Schistosoma antigens. This work is available at "http://memorias.ioc.fiocruz.br/issues/past-issues/item/955-anti-malaria-humoral-responses-in-children-exposed-to-plasmodium-falciparum-and-schistosoma-haematobium". There exist one paper in AMA1 comparing cross reactivity between proteins expressed in viral and bacterial systems" http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165491/"
I found this paper (linked below) with the following: " The monoclonal antibody F8.12.19, raised against the recombinant ectoplasmic region of AMA1 from Plasmodium vivax, cross-reacts with homologues from Plasmodium knowlesi, Plasmodium cynomolgi, Plasmodium berghei and Plasmodium falciparum, as shown by immunofluorescence assays on mature schizonts."
J Mol Biol. 2007 Mar 9;366(5):1523-37. Epub 2006 Dec 16.
Cross-reactivity studies of an anti-Plasmodium vivax apical membrane antigen 1 monoclonal antibody: binding and structural characterisation.
Igonet S, Vulliez-Le Normand B, Faure G, Riottot MM, Kocken CH, Thomas AW, Bentley GA.
The ectoplasmic region, which can induce protective immunity in animal models of human malaria, is a leading vaccine candidate that has entered clinical trials. The monoclonal antibody F8.12.19, raised against the recombinant ectoplasmic region of AMA1 from Plasmodium vivax, cross-reacts with homologues from Plasmodium knowlesi, Plasmodium cynomolgi, Plasmodium berghei and Plasmodium falciparum, as shown by immunofluorescence assays on mature schizonts