Oral sucrose seems to be not sufficient; more integrated strategies like sensorial saturation or breastfeeding or a combination of oral sucrose and facilitated tucking seem more effective than oral sucrose alone
We use Sucrose 25% , facilitated tucking and sensorial saturation as well and it appears to be sufficient. Sucrose at a higher percentage or fructose may be the answer
holding skin to skin with mother/father; suckling at the breast; expressed breast milk by spoon, cup or oral syringe. all can be helpful and avoid the problems associated with the intake of high sucrose bolus.
Use of pacifier, swaddle. Also it is important to provide a controlled noise/light environment and reduce the interventions (dxt) to decrease over reactive response.
We use sucrose 24 % associated with pacifier or sometimes breastfeeding and skin to skin contact on the mother for procedures as inserion of peripheral access or gastric tube
I think it has to be combination of many factor for example before putting iv line one can even start introducing her or himself to baby with gentle stroke to fingers. Plus sucrose with pacifier and tranquil environment which helps further to relax and calm the baby.