Do you have some scientific data about sunitinib in patient with CKIT-mutated melanoma progressed on imatinib (Brain mets) vs imatinib dose increase?

More Igor V Samoylenko's questions See All

Strong and extreme winds in the Arctic?

Hello everybody! Looking for a good source of information on strong and extreme winds in the Arctic (monthly values, annual extremes etc.). The form of maps (with isolines) will be most...

25 January 2021 8,984 4 View

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Dear Colleagues, I need your help. In book (can be found in Internet, free) Todhunter, I., & Pearson, K. (1893). A History of the Theory of Elasticity and of the Strength of Materials (Vol....

26 December 2020 433 1 View

Combine several datasets?

Dear colleagues, I would appreciate your advice on the following issue. Let's say, first I had investigated expression of Prot1 and Prot2 in tumor tissue, it's association with relevant clinical...

31 October 2020 4,875 2 View

Does the quantum vacuum have analogies in mathematics?

Take, for example, such a concept as a minimum flow, that is, a gradient vector field, the level surfaces of which are the minimum surfaces. Then the globally minimal flow, evolving to an...

13 September 2020 8,593 13 View

Can AI be emotionally intelligent (whatever AI, emotional, or intelligent may mean to you)?

Can AI be emotionally intelligent (whatever AI, emotional, or intelligent may mean to you)? Research addresses machine recognition and modeling of human emotional expression, including the...

11 September 2020 5,158 5 View

Where was Fischerella sp. PCC 9339/Fischerella musciola (UTEX1829) isolated?

Dear colleagues, I am currently comparing some genomic features in different representatives of Fischerella genus isolated from different eco-types. Unfortunately, neither PCC nor UTEX collection...

11 July 2020 4,003 12 View

Will DNA degradate if left over weekend during tissue lysis in extraction methods ?

Hi, Question occured while discussing with colleges if it's safe to leave tissue lysis over weekend, because there are no problems to left overnight which can even be written in some extraction...

09 July 2020 4,084 4 View

Are these claims about compactification true?

1. Do I understand correctly that closed curves on a 3-dimensional torus are represented as closed ribbons lying freely (with the possibility of inverting) on a classical torus? 2. Do I understand...

20 May 2020 799 3 View

Possible optimization algorithms for fitting a nonlinear model with no analytic solution (contains integrals that can only be solved numerically)?

I would be grateful for suggestions to solve the following problem. The task is to fit a mechanistically-motivated nonlinear mathematical model (4-6 parameters, depending on version of assumptions...

14 April 2020 2,117 12 View

How can I design a PBG substrate microstrip antenna in Matlab?

I'm using antennaDesign tool box of Matlab to design a insetfed Microstrip antenna. Now I want to compare the results with the same antenna, but with a PBG substrate. How can I do this?

10 April 2020 7,257 4 View

Which Journals would you advise to submit a Letter which briefly talks about neurosurgical treatment of neuro-oncological patient during Sars-COV-2?

Possibily not an open access journal which does not add any publishing costs once being accepted. Thank you in advance

09 February 2021 717 6 View

What's wrong with this fronzen section of mice melamona tissues?

I met a problem when I was doing frozen section for mice melanoma tissue. Based on the confocal results I got as attached, seems like the cell structures are destroyed (looks like a network) and...

31 January 2021 8,464 4 View

Anybody with an idea for a metastatic murine cancer cell line?

Hello, are there any murine cancer cell lines out there that once injected subcu will metastasize to the liver? I know there is LLC and some melanoma cell lines that will go to the lung....

08 January 2021 6,203 3 View

Where I can find DermIS and DermQuest datasets for skin cancer (Melanoma)?

actually I searched the related web sites, but the quantity of samples are maximum 20 or 30 pictures, but I saw in articles that there are datasets from theses 2 sources with enough number of...

07 December 2020 8,145 1 View

Why is SV40 not considered an oncogenic virus?

Hello, SV40 is not considered an oncogenic virus in this review:Oncogenic viruses and cancer Why is SV40 not considered an oncogenic virus when it produces the large T antigen, which is...

04 December 2020 8,374 5 View

Where can I find a CSV of melanoma data?

Hi all, I am looking for a dataset of melanoma patient attributes. So for example age, sex, history of melanoma, history of cancer, family history, benign or malignant. I hope my question was...

13 November 2020 2,334 1 View

Could the desmin mutation in myofibrillar myopathy be caused by an infection?

A patient with desminopathy (mutation Thr341Pro DES in a heterozygous state) with the progression of the disease has a decrease in taste and smell, immunosuppression, and an increase in IgA in the...

02 November 2020 5,886 6 View

Does anyone has experience with Dextran-FITC uptake by cancer cells?

Please share the protocol for antigen uptake assay by cancer cells. I want to use Dextran-FITC to track the endocytosis by cancer cells. If anyone has the protocol or any suggestions kindly share.

25 October 2020 469 3 View

What's the difference between Photoacoustic (PA) and Photoacoustic Flow Cytometry (PAFC)?

I was asked to do a presentation on the following paper: Juratli, Mazen & Menyaev, Yulian & Sarimollaoglu, Mustafa & Siegel, Eric & Nedosekin, Dmitry & Suen, James &...

14 October 2020 8,346 1 View

Ideal sample size calculation for a descriptive study ?

I wish to estimate the expression of two types of markers by immunohistochemistry in the biopsy specimens of a particular type of cancer, and correlate their expressions with clinical parameters...

20 September 2020 9,662 6 View