Do you have some scientific data about sunitinib in patient with CKIT-mutated melanoma progressed on imatinib (Brain mets) vs imatinib dose increase?

More Igor V Samoylenko's questions See All

Why don't I have a PCR product with proofread polymerase?

Dear Colleagues, I have the following problem: I’m trying to amplify a cassette with a resistance gene (about 2 kb) from the yeast genome, so that I can then insert it into a plasmid. With Taq...

03 July 2024 105 11 View

Staining of isolated mitochondria tecnique?

Greetings, dear colleagues! Do you know any technique utilizing some ~ordinary molbiol lab reagents (not the commertial kits for isolated mitochondria staining) that will allow isolated...

07 June 2024 5,909 0 View

How proving Riemann Hypothesis will fasten the development advanced self learning algorythms?

If Proven how Riemann hypothesis will help the development of AI and maybe help us create real advanced self-councious algorythms?

05 June 2024 9,787 3 View

Which relevant sources can be used to find reports on the scope of donations to political parties within the EU?

We are working on gathering raw data and information about the scope/share of private donations and public funding to pilitical parties that sometimes in EU is a part of responsibilities of...

16 April 2024 5,178 0 View

Is it possible to know the dwell time for a given isotope/mass from a raw LA-ICP-MS trace elements data file?

I have a dataset of trace elements LA-ICP-MS analyses with raw data, which consists of a set of a single file for each spot analysis. Each of these files has some columns (masses) and plenty of...

24 March 2024 898 6 View

Why are p-values of Durbin-Watson statistics different for dwtest and durbinWatsonTest in R?

I am analyzing some time-series data. I wrote a script in R and used two methods from two different packages in R to calculate the DW statistics and respective p-values. Surprisingly, for the...

14 March 2024 6,127 1 View

How to normalize expression data with SEM?

Greetings. Probably the question is not complex at all, but can't find an answer. If I have RT-qPCR data of gene expression in a sample with multiple analitycal replicates - to compare it to data...

13 March 2024 7,640 1 View

How can I add my papers with my name with different spelling?

In particular, I have few papers with spelling Agranovskii. Thank you

05 February 2024 3,764 1 View

How to generate causal effect estimates from causal forest in the grf R package for continuous treatments?

I am using the grf R package (https://grf-labs.github.io/grf/reference/causal_forest.html) to obtain causal effect estimates for a continuous treatment variable. The package description says:...

15 January 2024 1,990 0 View

What does a 4-dimensional Euclidean space look like from the point of view of a 3-dimensional observer?

If we keep in mind that R^{4}=R^{+}xS^{3}=R^{3}*RP^{1} where * means a direct product with a singularity at the zero point of a 3-dimensional Euclidean space in which the projective line is...

30 December 2023 9,110 1 View

Is there any resource where I can find the quantification of transposable elements among TCGA samples?

I am interested in analyzing the correlation between the expression of a set of genes and transposable elements (TEs) in cancer. However, despite there are multiple online databases for gene...

21 January 2024 6,156 1 View

Any specific articles on relationship between exercise, the gut microbiome, and the risk of developing certain types of cancer?

Relationship between exercise, the gut microbiome, and cancer is complex and multifaceted. Factors such as the type and intensity of exercise, individual differences in gut microbiota, and genetic...

14 December 2023 5,976 3 View

Radiation Oncology Online Validation?

I have an (online questionnaire) in Radiation Oncology field need to be validated by radiation oncologists, any one can help?

13 December 2023 5,405 1 View

Publishing in Oral Oncology Reports, is it Ok?

Greetings all, I'd like to ask if 'Oral Oncology Reports' as a companion journal to the well-known 'Oral Oncology' journal would be a good choice to publish? The journal is a very recent one .....

13 December 2023 6,325 3 View

How to prevent localized tumor formation around the eye when R.O. injecting B16F10 melanoma cells into Bl/6 mice?

In order to study melanoma lung metastasis in aged hosts, we did RO injection of B16F10Luc2 melanoma cells (expressing firefly luciferase) into both young (16 weeks) and old (>2 years) mice....

03 October 2023 6,198 1 View

What is the link between ascites, nodular peritoneal thickening and serosal carcinoma, ovarian cancer, high CA-125? Treatment options?

A very Emergency case, The Mother of my best friend, the results of her MRI said that she had nodular peritoneal thickening that suggested peritoneal serosal carcinoma, and ovarian cancer, also...

01 October 2023 3,590 6 View

Pmel adoptive transfer: homozygous vs heterozygous?

Do I understand correctly that heterozygous Pmel mice have twice as less cells that carry anti-gp100 TCR? This should be right because of the allelic exclusion. If so, can one combine both homo...

05 September 2023 260 1 View

What are the future research directions and emerging trends in the field of machine and deep learning for brain tumor identification?

What are the future research directions and emerging trends in the field of machine and deep learning for brain tumor identification, and how can they pave the way for novel applications and...

05 August 2023 926 0 View

Two resarch gete email an ideas??

I have asked earlier to remove my other account in researchgate.net My own account is made by myself (Tampere University, TaU, Finland) and the other one by hospital research center (Tampere...

31 July 2023 5,059 0 View

SK-MEL-103 STR profile?

Hi all. Do you know the STR profile of SK-MEL-103 melanoma cell line? I guess it is not available from ATCC... Thank you.

16 May 2023 3,956 1 View