While measuring zeta potential of nanoparticles in 0.001 M NaCl or 0.01MKCl , do we need to adjust pH of solvents to around alkaline conditions or pH won't matter here?
pH and ionic strength both influence zeta potential as it is a property of the whole sample system, i.e. depends on the solvent, ionic strength, type of ions, pH, additives...
When determining the zeta potential of nanoparticles in 0.001 M NaCl or 0.01 M KCl, changing the pH of the solvent to the proper level, including alkaline conditions if necessary, is important. This is because the surface charge of nanoparticles influences the zeta potential, which varies with pH due to changes in surface group ionization. If the nanoparticles' surface charge or stability is pH-dependent, altering the pH will offer a more precise measurement of their zeta potential under specific conditions relevant to your research or application.