im doing acute toxicity based on OECD 423 guideline...i have not seen any advice to get blood sample for hematology and biochem study in that guideline...so just to get opinion from others, do we need to do blood study in acute toxicity of plant extract?
Haematology is one of the important parameter related with animal experiments, because plant drugs will change the basic physiology of the animal, the changes will suggest you the effect of your drug. My one more suggestion is that go with histological studies also, it will provide you more supportive data....
Yes.Mr Azri.It is very important to assess the effects of the plant extract on haematological or hepatospecific indices.Attached is a copy of an article with some information on the same.
Article Acute toxicity of the aqueous-methanolic Moringa oleifera (L...
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