Hello!

The typical instrument for dioxin analysis at trace levels is a High Resolution GC-MS based on sectorfield technology. Normaly these instruments work in the femtogramm range at resolution 10.000 . See www.thermoscientific.com/dfs as an example for an instrument. For these relatively expensive instruments You will need also an experienced person in charge. Please don't forget that dioxin analysis needs also sophisticated sample preparation.

You may use also other instrumentation like quadrupole GC-MS, GC-triple quad or GC-TOF, but the quality of data is limited.

Ludwig

Thank you very much for your participation Mr.Ludwig.

The determination of dioxins and related compounds requires a

method that provides extremely high sensitivity and selectivity.

The significant sensitivity improvements of sector instruments

during the last two decades naturally enforced the high-resolution

gas chromatography (HRGC) in combination with high-resolution

mass spectrometry (HRMS) as the ‘gold’ standard method. In

selected ion monitoring (SIM) mode, HRGC-HRMS (10,000 resolution) can achieve detection limit at the femtogram (10-15

g) level for most of the dioxin congeners. However, alternative techniques

based on MS instruments exist. The most studied alternative

method is GC coupled to bench-top low resolution quadrupole ion

storage mass spectrometer (QIST-LRMS). The loss in mass resolution is counter-balanced by a gain in specificity in tandem mode

(MS/MS). Emerging technique as comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry (GCxGC-TOFMS) offers series of advantages that can be used

in the field of dioxin analysis.

http://bictel.ulg.ac.be/ETD-db/collection/available/ULgetd-04022008-071117/unrestricted/10publication3.pdf

Thank you very much Mr. Khodir

High resolution GC with HR-GCMS are the choices. Sample preparation and extraction method and analysis of certified samples are very very important factors that reflect the sample analysis quality. you may lose most of the sample due to due bad extraction procedure.

Thank you Mr.Radwan