Catechol 2,3-dioxygenase and catechol 1,2-dioxygenase.
More studies are needed to further elucidate oxygenase enzymes that are responsible for triclosan degradation.
http://oaktrust.library.tamu.edu/bitstream/handle/1969.1/ETD-TAMU-2012-08-11865/LEE-DISSERTATION.pdf?sequence=2
Hi Ezinne,
Trichlosan cannot be fully degraded (mineralized!) by bacteria because it is a bactericide. But there are tolerant bacterial strains which have extrusion pumps to get it out of their cells (given the fact that these cells have another source of carbon and energy to drive them). Since the compound is a halodiphenyl ether, diphenyl ether-degrading bacteria can attack triclosan, cleave the ether bridge and partly degrade some of the catabolites. Also the peroxidase systems of several fungal species can oxidize Triclosan but not mineralize it completely.
Attention: all papers claiming triclosan degradation are quite obscure, in my experience!
These days work is in progress with Laccase enzymes, which have been proved to degrade Triclosan to significant levels.
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