Dear Kamesh Krishnamoorthy

Pls. find the attached files, will answers your questions

http://genomebiology.biomedcentral.com/articles/10.1186/s13059-015-0799-6

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598821/

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653885/

http://www.sigmaaldrich.com/technical-documents/articles/biology/crispr-cas9-genome-editing.html?gclid=CPaBzaWNgM8CFVQaGwodjs8PvQ

http://journal.frontiersin.org/article/10.3389/fpls.2016.00475/full

http://www.nature.com/articles/srep26912

http://www.ncl.ac.uk/sage/study/postgrad/dta/documents/2016-Howard-74.pdf

https://www.sciencenews.org/article/gene-drives-spread-their-wings

http://www.nytimes.com/2015/12/22/science/gene-drives-offer-new-hope-against-diseases-and-crop-pests.html?_r=0

http://wyss.harvard.edu/viewpage/556

http://www.whatisbiotechnology.org/science/crispr

http://mbio.asm.org/content/5/2/e00877-14.full

Hoping this will be helpful    

Prof. Houda Kawas

Thanks a lot sir

you most welcome

Houda