Could you recommend an in silico tool to predict the hemolytic potency of a drug?

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Bakr Mohammedali

thank you for your answer but I need to know if may molecule have a hemolytic activity as a side effect or not

Simone Brogi

Hi, maybe this online tool could be useful for your purpose. You can find it at this link:

http://crdd.osdd.net/raghava/hemopi/design.php

and this is the main page

http://crdd.osdd.net/raghava/hemolytik/

Sincerely

Simone

I want to know the hemolytic activity of molecules no Peptide

I suppose that does not exists for small molecules. You can built a 3DQSAR model to predict this activity taking into account the experimental data.

Eduardo Borges de Melo

If you have EC50 values of the compounds or some similar biological activity, try a QSAR study. I suggest the QSARINS program, available for free. www.qsar.it