Could you please share some advices or road map for someone new to the field of PBPK modeling?

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Tirtha Nandi

Understand compartmental PK modeling→ and classical 1C or 2C or 3C models→ then try to understand the difference between these models with the PBPk models. I would also suggest reading some reviews on PBPK models.

Stephen Hall

Find a model in the literature that corresponds to your need. Draw the schematic. Write the equations.

Ask an experienced PBPK scientist to go over your equations to discuss pros and cons of your assumptions.

Slowly build up the complexity and repeat.

Ahmed A. Abdelgalil

Thank you all for your valuable input.