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Article Cervicitis amongst teenage sex workers within Benin City m...
Yes.Recent reports suggests significant association between inflammation and neoplasia. Please go through the review of Sergei I. Grivennikov for the biology behind it. (Cell 140, 883–899, March 19, 2010 ª2010 Elsevier Inc.) Microscopic analysis of the cells or tissue samples of CIN often confirms the association of chronic inflammation with these lesions.As the role of persistent infection with high risk HPV has been well established, associated inflammation can also be expected.
Yes
The HPV virus has to reach the basal cells of the cervix. Therefore, there must be some form of break in the epithelium for the HPV to reach the basal cells. Cervicitis is one way in which there can be a break in the epithelium. A similar situation exists in throat cancer and the relationship between smoking and drinking spirits. The smoking and spirit drinking results in a break in the epithelium and therefore HPV can reach the basal cells. In cervical cancer it does not have to be cervicitis and the process of metaplasia is also thought to be associated.
Dear Odega. It is a very interesting question. Recently in a cohort study the authors showed an important association between Chlamydia and CIN 3.
Sex Transm Infect. 2014 Apr 12. doi: 10.1136/sextrans-2013-051431. [Epub ahead of print]
Chlamydia trachomatis and risk of cervical intraepithelial neoplasia grade 3 or worse in women with persistent human papillomavirus infection: a cohort study.
Jensen KE1, Thomsen LT, Schmiedel S, Frederiksen K, Norrild B, van den Brule A, Iftner T, Kjær SK.
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