If your question is, can I use single crystal data for describing those of polycrystalline materials, then I can help. Yes, you can use the dielectric tensor (not the refractive indices, because in general the dielectric tensor is the specific property) to describe the optical properties of microcrystalline samples. If the crystallites have diameters in the 100 nm range, you might have to slightly change the damping constants (the lifetimes) e.g. of the phonons. Note that the optical properties and the way the dielectric tensor is reduced to a scalar for random orientation depends on the resolution limit of the light, i.e. it depends on the wavelength (there are at least three different kinds of optical isotropy.... ;-). You might want to read:
Article Modelling IR spectra of single-phase polycrystalline materia...
Article New Method of Modeling Infrared Spectra of Non-Cubic Single-...
Article Interpretation and modeling of IR-reflectance spectra of gla...
Article Modelling IR-spectra of single-phase polycrystalline materia...