Isolation is currently the best preventive solution because Coronavirus has a high level of infection and there is no vaccine or any other fully effective Coronavirus drug yet. In addition, it is estimated that many people who do not have disease symptoms, do not get sick, but they may already be infected with Coronavirus, so that the pandemic does not expand, all people should follow the recommendations, i.e. you should wash your hands often, stay at home and limit the exit from home to the necessary minimum. people who show any symptoms of a cold, such as a runny nose or cough, should not leave the house because they may be infected with Coronavirus, even though they are not seriously ill. The idea is to minimize the extent of the spread of the Coronavirus pandemic and currently isolation, home quarantine is the best solution for all people, regardless of whether they are sick or not.

Best wishes.

Dariusz Prokopowicz

Mutations (happening daily, likely) of COVID-19 would play just a small role in the arguments here. The point is that, to a good approximation, one can only be infected once -- for two to three years, at least. Also, it is a lung illness, thus a winter-weather disease. Mutations or not, isolation is the best measure. As the virus spreads, isolation reduces the number possible propagators. To help fellow citizens, take care of yourself and isolate even when in good health. The Internet helps.

The COVID-19 comes from animals, it is zoonotic, and will likely mutate after infecting humans, to survive. Like the Kansas flu (aka the Spanish flu) that came from animals, the second wave was far more deadly, after the first mutation. This can happen with COVID-20, but the arguments remain -- isolation is the best way to handle it. See the good experience of SF USA with the Kansas flu of 1918, first wave.

Vegetarianism is a good way to reduce zoonosis, and avoid future infestations. Eating animals is subjecting the humans to higher risk.

There is currently no vaccine to prevent coronavirus disease 2019 (COVID-19). The best way to prevent illness is to avoid being exposed to this virus. However, as a reminder, CDC always recommends everyday preventive actions to help prevent the spread of respiratory diseases, including:

Avoid close contact with people who are sick.

Avoid touching your eyes, nose, and mouth.

Stay home when you are sick.

Cover your cough or sneeze with a tissue, then throw the tissue in the trash.

Clean and disinfect frequently touched objects and surfaces using a regular household cleaning spray or wipe.

Follow CDC’s recommendations for using a facemask.

CDC does not recommend that people who are well wear a facemask to protect themselves from respiratory diseases, including COVID-19.

Facemasks should be used by people who show symptoms of COVID-19 to help prevent the spread of the disease to others. The use of facemasks is also crucial for health workers and people who are taking care of someone in close settings (at home or in a health care facility).

Wash your hands often with soap and water for at least 20 seconds, especially after going to the bathroom; before eating; and after blowing your nose, coughing, or sneezing.

If soap and water are not readily available, use an alcohol-based hand sanitizer with at least 60% alcohol. Always wash hands with soap and water if hands are visibly dirty.

Isolation is currently the best preventive solution because Coronavirus has a high level of infection and there is no vaccine or any other fully effective Coronavirus drug yet. In addition, it is estimated that many people who do not have disease symptoms, do not get sick, but they may already be infected with Coronavirus, so that the pandemic does not expand, all people should follow the recommendations, i.e. you should wash your hands often, stay at home and limit the exit from home to the necessary minimum. people who show any symptoms of a cold, such as a runny nose or cough, should not leave the house because they may be infected with Coronavirus, even though they are not seriously ill. The idea is to minimize the extent of the spread of the Coronavirus pandemic and currently isolation, home quarantine is the best solution for all people, regardless of whether they are sick or not.

Best wishes.

Dariusz Prokopowicz

I agree with the view of Dariusz. We must also pursue the course of high hygienic practices and sanitization in addition to isolation. Stay protected all RG family.

All: In addition to isolation, which is an "all or nothing" proposition, one can more realistically practice also "extensive social distancing" when needed, where you create a barrier of defense even when exposed more.

Avoid crowds (three is a crowd) when you break isolation. Only when needed, not when wanted, and keep 2 m (6 ft) away from people (use stairs, not elevators). Keep groceries in the car or in an isolated bag in the refrigerator, for at least 48h, to decontaminate by itself (any possible COVID-19 is expected to die, may extend to a week). Wash if you need it first. Wait in the car, and let the younger do the shopping. Don't touch.

You will know when it is safe again. Now, it may be a crisis, but don't forget that tomorrow is another day, coming soon.

All : The Earth that will be next will accept and embrace work/study/voting/living/etc online.

This COVID-19 is real, a highly contagious pneumonia, and will decrease loneliness, vaping, smoking, marijuana, so-called "recreational" drugs, promiscuity, and idleness. It will decrease suffering.

Keep isolated, COVID-19 is transmitted by persons and surfaces that persons touch or cough on. Not by air.

There will be a treatment in the future, and immunity in the DNA and epigenetics. But this will take time, it maybe like leper or the Kansas flu were -- but today, no one dies of them. This too, will end. It is a finite number of steps to go through.

People can use their car or room as a sterilizer -- just let it stay on the trunk for 3 days. It should be enough to kill any circumstantial virus.

Shop online only, there are aggregator services one can use, and they deliver -- saving time and health, and cost less. Reduce your exposure to people and surfaces you touch less than 2 meters away.

Try to find online activities/work for you.

The future has arrived. It is not random, it is chaos -- utterly predictable. It s a different way of living -- and will be happier and more productive. The online work extends to social, so your friends and family are no longer just local.

There is one caveat: What about depression, which dramatically reduces immunity?

But there is the opposite view from Italy, from a Russian emigrant from https://www.youtube.com/watch?v=8kAsiQvXqYM

Italy. Operation Corona virus. Administration of different regions of Italy. About the media.

There are one drawback is the video in Russian.

GF: Depression seems to more prevalent _without_ isolation, because the real effects are more severe and widespread. The data from NY supports that, versus California.

This is mainly a droplet disease and corona virus is very much infectous. There is no such vaccine for this virus nor a proper medical treatment, So for now isolation is the best preventive action we can take to avoid this virus infection.

All: See also https://www.researchgate.net/post/Reasons_FOR_AGAINST_using_chloroquine_or_hydroxychloroquine_against_COVID-19

Coronavirus , as a most likely engineered product has attacked they very nature of human beings which is their habit of socialization. Shutting ourselves up, choosing to be isolated, is actually the only way to be saved from the cruel clasp of COVID 19 even though it strikes at the foundations of sociability. Right now, it seems that isolation is a practical strategy in keeping off the virus and preserve the fire of hope burning, wishing that people of the world would once more experience and feel the safety of health security and wonderful merits of socialization.

Isolation, home quarantine and other instruments, systems, recommendations for anti-pandemic safety are important in the development of such a pandemic as e.g. pandemic SARS-CoV-2 coronavirus pandemic causing Covid-19 disease, because in this way the process and scale can be significantly slowed down subsequent infections and thus the development of a pandemic. By slowing down the development of a pandemic, healthcare and healthcare institutions gain extra time to better prepare themselves for the next phases of pandemic development. On the other hand, isolation, home quarantine and other instruments, systems, and anti-pandemic safety recommendations do not stop the development of a pandemic and its rapid extinction. However, they play a particularly important role in the process of slowing down the development of a pandemic. The extinction of a pandemic caused by viruses characterized by a high level of contagiousness occurs primarily through a significant, usually overwhelming majority of society, natural collective resistance to a specific virus and this process can be accelerated by the creation of vaccines and / or other effective therapeutic therapies.

Greetings,

Dariusz Prokopowicz

All: Today, there is already light at the end of the tunnel for the COVID-19 infection, from the viewpoint of the mathematics and physics of evolution.

The COVID-19 virus needs to evolve. If it is too lethal, it kills the host before it can spread more -- highly lethal virii, like EBOLA, SARS, and MERSA, instead of super-spreaders in infectious diseases (as feared) petered out, killing the host too quickly and isolating themselves.

Having less lethality allows the virus to become even comensal, to live together with the host, as we have millions of virii, bacteria, parasites, and animals who co-live with the human body, performing various functions, and compose most of the DNA/RNA of the human body.

Thus, due to forces of evolution, the COVID-19 virus must evolve and become less lethal, and even useful, or die off. But then, hopefully, we will also have learned our lesson in evolution, this time mental, in society, and in nutrition.

We should respect all life forms, and do not eat meat anymore, avoiding such zoonotic spillovers. India is an example to humanity, in that. Universal health care, an inalienable right of a society to its members, should help us become more resilient in our life and business. Pollution, did, can, and should decrease, including that of CO2. Online learning reveals itself as more efficient than class instruction can ever be, because it is repeatable and personalized at inception. Online business can scale much better than limited brick-and-mortar, and at less cost to all. And, many more.

Thus, having done in a few months what humans generally said was impossible, the COVID-19 virus should get a medal of good services and another of instruction, ushering in a better 21st century.

A group of Chinese scientists report the isolation of two human monoclonal antibodies with the potential to treat and to prevent SARS-CoV-2 infections, the causative agent of COVID-19. The work is described in a manuscript made available by Nature Cellular and Molecular Immunology.

The two monoclonal antibodies block binding of the virus to the receptor preventing entry.

Such antibodies hold great promise for treatment as they are expected to prevent the virus spreading from cell to cell. The antibodies are also likely to protect those exposed, especially healthcare workers, from infection at least for a limited time. In both cases, the drugs would be administered intravenously.

Covid-19 is highly infectious with number of infected doubling in 2-5 days without contact avoidance methods, and has the mortality ration about 1% or more depending on the situation (2.5%-5%). As there is no medicine and no vaccine, the number of dead becomes quite high unless quarantine methods are applied. There are currently two strategies: the one in Sweden where they think that herd immunity can be reached and is the best way, and the one trying to stop the epidemic by contact avoidance and finding infected. The latter strategy seems to work in many countries. There is no evidence that herd immunity can be gained. It is known from other coronaviruses that reinfections are common with coronaviruses: either the human immunoresponse is insufficient for these viruses or immunity is of short term. A recent study in Finland confirmed what had been suspected: there may be about 20 times as many people who have antibodies to the virus than the known number of infected, but these people do not have enough antibodies for immunity. The number of people who get immunity is apparently only twice as many as are known to be infected. This gives the mortality ration of about 1%. Calculating from 1% and 60-90% infected shows that trying to gain herd immunity causes very many deaths, and still the protection may not work. Therefore contact avoidance and trying to stop this epidemic is the best strategy so far. This pandemic, if it continues long, will seriously harm the economy. Therefore the duration of the pandemic should be made as short as possible.

Social divergence is necessary because an infected person spreads when he coughs virus-laden air in the air. Others become infected because they breathe in the spray by breathing, or by touching a surface where the spray occurred, then touching the eyes, nose, or mouth.

To prevent this disease from spreading

I think that a good solution is to keep isolation but voluntary for everyone - everyone should understand and realize and make a decision that meetings with friends should be limited.

The quarantine will not save, but will only stretch the process of infecting people during a time, because sooner or later everyone will be infected. Now it seems that the authorities realized that it is pointless to do this and therefore allow all industrial enterprises to work, for example, in Moscow from May 12, 2020. However, this is not a tragedy, because only some share of percentage will suffer seriously, mainly due to concomitant diseases and some share of them unfortunately will die. However, it seems that these people would die sooner or later in the near future, because the coronavirus simply gave complications of these diseases. However, the vast majority of people will not even notice the coronavirus in their body, and even they will not understand that they are sick with the coronavirus if they are not tested. Another part of people will be ill in a mild form. Therefore, do not be discouraged. We must take into account statistics on the number of deaths per 100 thousand people, and these statistics are some fraction of a percent. However, everything will finally become clear when this psychosis passes and the final results are obtained.

To protect the transmission of droplet like virus, isolation till to over its normal life time is an effective way as revealed by experts.

GF: You seem to be forgetting that the virus can mutate and become less lethal, so isolation can give us all more time to wait for that -- and also wait for advances on treatment or vaccines. It is not a static threat... we can reduce the threat for all while waiting, and have that much less death and suffering. Isolation is more productive, and allowing more productivity.

Even the common cold is now less likely, less common, less deadly. But it is not that we were oppressed, we just did nothing about it. People should not work sick, for example, and serve others... We can't keep the same bad habits, we need to change. To win, or to win. Stagnation seems not to be an acceptable option anymore.

WL: It must not be voluntary for isolation to work. It is a social duty. Likewise, one cannot drive a car or pilot a plane without a license.

All: Isolation is life -- there is no better way to avoid spreading the coronavirus COVID-19 without control. It is the only control we have.

All: A usually hidden point, but that affects all points in a list, is how patient information is kept private, for example in concerns around making sure that only a desired doctor knows your case, and test results are truly private (COVID or no COVID?, pregnant or not pregnant?}.

The current model, even with HIPAA and HITECH Safe Harbor, is to make the patient accept whatever is provided in a DISCLAIMER and sell the data even weakly anonymized. That should change. Why?

Customers are learning, through COVID as a shortcut, that financial and reputation worries (all short-term) should not cloud over matters that can result in "life or death" situations (long-term).

One should not sign off on a VBAC (even with 2% chance of death) if there is a C-section (short-term risk) recommended; as death or uterine breach may result (long-term risk) and although improbable, it has no solution. The same with breaking isolation under COVID (let us assume a 2% chance of death), as death may result (long-term risk) and although improbable, it has no solution yet (no hydroxicholoroquine, please).

Even without universal health care, this does not make sense -- it is not ethical.

The cost, time, and nuisance of testing can fall to 25% less, immediately, just by following:

https://www.linkedin.com/posts/tiffany-v-gerck_covid19-risks-costoptimization-activity-6672171443247308800-T41m

Protect yourself and keep your distance......................................

All: In COVID times, I am working on -- in Physics, Engineering, and Math at Planalto, in cybersecurity at zsentry.com and safevote.com, and offer here our research items for collaboration.

It requires no use of personal protective measures.

The coronavirus pandemy will end when humans realize their intelligence can conquer anything, not just cyber defenses, or hacking contests, or loss. We have to learn to unite, to work in collaboration, adding NOT competing. A new era of progress wIll be created, and the leeches will be gone.

Isolation is the best and quickest method to shrink the growth of the infectious population because even if a good vaccine is discovered and the isolation is not maintained, it is obvious that susceptible individuals will still be infected by the Infectious people and to verify this i decided to create a model and randomly assign some parameters to it and simulate with python software. My observation is that the only easier way to shrink the infectious population is by isolation, i also increased the parameter for efficiency of vaccine to 9.0 and my observation is that the virus will still persist in the community for a longer time but an increased isolation of 0.8 was able to shrink the the growth of the epidemics to it's minimal to a point where no susceptible individual is being infected.

Isolation brings in the problems of lack of diversity and variety. Forced lack of diversity and variety is a reminder why we need each other.

To break the chain

The virus that causes COVID-19 is spreading from person-to-person. Someone who is actively sick with COVID-19 can spread the illness to others. That is why CDC (Centers for Disease Control and Prevention) recommends that these patients be isolated either in the hospital or at home (depending on how sick they are) until they are better and no longer pose a risk of infecting others.