New scary large valid studies recently showed an increased prevalence of
diabetes mellitus during the pandemic - I am convinced we will see an increase of
Hidrosadenitis Suppurativa, Psoriasis and Atopic Dermatitis ?
In marts 2021 I wrote
Corona COVID-19 obesity and increase in autoimmune diseases
Obesity appears to be a major environmental factor contributing to the onset and progression of autoimmune diseases. In Demark we have registered a significant increase
In BMI especially in studies among schoolchildren
COVID-19 binds to ACE2-receptor and initiate a cascade of cytokine-activation inkluding IL1-beta, IL-12, TNF-alpha and especially an increase of IL-6 and might initiate a so-called cytokine storm.
Can prospective studies with patients with and without Corona COVID-19 theoretical show and increase in the incidence of autoimmune diseases in the Corona group , including our patients with dermatological conditions such as Hidrosadenitis Suppurativa, Psoriasis and Atopic Dermatitis ?
Are such studies of relevance ?
Kind Regards:
Carsten Sauer Mikkelsen
Specialist in dermato-venereology
According to a recent paper published in "Nature" by Sarah Esther Chang et al. titled: "New-onset IgG autoantibodies in hospitalized patients with COVID-19", more than 50% of hospitalized Covid-19 patients have new-onset autoimmunity manifested by autoantibodies.
https://pubmed.ncbi.nlm.nih.gov/34521836/
Nat Commun. 2021:14;12(1):5417.
doi: 10.1038/s41467-021-25509-3
There is increasing evidence worldwide that part of the late post-Covid syndrome includes a degree of new-onset autoimmunity.