Clinical chemistry

More Tsung-Chien Lee's questions See All

Gaussia Luciferase for Bioluminescence Tumor Monitoring in Comparison with Firefly Luciferase. Which is better?

Been doing searches to find the best paper to start understanding the advantages and disadvantages of each technology: Gaussia Luciferase for Bioluminescence Tumor Monitoring in Comparison with...

29 June 2024 9,856 1 View

Electrode polarography Single Scan and Cyclic Methods to Reversible, Irreversible Systems. figure 4 and 5?

Hello all, I am an undergraduate student major in Chemistry and freshman in electric chemistry, i am now reading a paper on ACS AC. i had a few question on explaining figure 4 and figure 5. My...

12 April 2024 7,820 0 View

Methods for precipitation potential evaluation for IV and SC administration in developing early formulations. Best Methods?

Looking for a more recent publication or review on Developing early formulations: Practice and perspective. More specifically methods for precipitation potential evaluation for IV and SC...

12 March 2024 8,564 1 View

How to sterilize materials coated on PP in situations where high temperature and UV cannot be used?

How to sterilize a polymer grafted with a photoinitiator before cell culture?

23 January 2024 9,548 2 View

Why mimicking physiological conditions or clinical situation important for translational research?

Write a short summary of 250 words on why mimicking physiological conditions or clinical situation important for translational research. (Free ChatGPT (July 13 2023 around 1100am JST) Answer from...

12 July 2023 3,737 1 View

Current state of the art for Dried matrix methods (DMM) and Microsampling for safety pharmacology and toxicology methods [See upcoming webinar] ?

Trying to understand better current status of Dried matrix methods (DMM) and Mircorsampling [updated question to include Microsampling (blood/plasma) and webinar details] - Aug 18 2022 - Thu, Sep...

26 April 2022 7,726 4 View

Is there a theoretical best time to dose lenalidomide (background updated Updated Jan 12th 2023) ?

" Given lenalidomide’s mechanism of action, it is intriguing that IMiDs and proteasome inhibitors are synergistic in the treatment of multiple myeloma.(24) Recent evidence suggests that this...

16 December 2021 3,086 8 View

Does anyone have more resources on this topic or thoughts about future advancements in implantable pumps?

I’m interested in the advancements in implantable and programmable micro infusion pumps and I found this recent publication in Drug Discovery Today Modulating target engagement of small molecules...

02 March 2021 8,205 3 View

Detrending speceis abundance data?

For an nxp matrix of species abundances, I have coordinates of the n sites. In order to use the species abundance data for spatial modelling or redundancy analysis, I note that in the literature,...

15 March 2020 2,209 4 View

Request Python code?

Request Python code from this article : Gender equity of authorship in pulmonary medicine over the past decade. THANKS!

08 August 2024 6,242 2 View

How to calculate CCS for Sodiated adduct ions and Multiply Charged Ions?

I'm currently working on calculating the collision cross section (CCS) for various ions, and I'm facing challenges when dealing with sodiated and multiply charged ions. Most of the resources I’ve...

08 August 2024 8,329 0 View

Why does everyone use vs code?

Visual Studio Code (VS Code) has become a popular choice among developers for several reasons: 1. **Free and Open Source**: VS Code is free to use and open source, making it accessible to...

07 August 2024 7,013 4 View

Is an invitation to join the editorial board of Clinical Cardiology Updates a scam?

I received an e-mail invitation to join the editorial board of Clinical Cardiology Updates. While I have published a few articles related to cardiovascular disease, there are lots of colleagues...

06 August 2024 8,981 8 View

How can i do multivariate Time Series forecast using MLP, ANFIS and LSTM?

I need the python code to forecast what crop production will be in the next decade considering climate and crop production variables as seen in the attached.csv file.

05 August 2024 2,977 3 View

Inquiry on Maximum Nucleic Acid Volume for 2.5 mL Liposome Solution?

I am currently working on a project involving liposomes and need to determine the maximum volume of siRNA that can be added to a 2.5 mL liposome solution with a total lipid concentration of 10...

30 July 2024 6,420 1 View

Can anyone please provide me the full text article of this clinical Trial?

Roflumilast Cream Improves Signs and Symptoms of Plaque Psor...

29 July 2024 5,250 0 View

How can I use DFT-D3 correction ( Siesta version 5.0.1)?

Dear Siesta Users, I installed Siesta 5.0.1 and I want to use Grimme's D3 correction. According to the 5.0.1 manual, I could use a few parameters to include the D3 correction in the...

27 July 2024 5,748 0 View

What is your major research area?

My major research area is clinical research and basic research of thyroid and parathyroid.

26 July 2024 3,639 14 View

EDC carbodiimide and NHS easter 's half life among different pH?

It has been long known that EDC carbodiimide and NHS easter's half life agains hydrolysis are highly related to pH. However, very surprisingly, not yet found a paper giving a table/chart of their...

25 July 2024 8,738 0 View