Does anyone know about a reliable CD8 T cell epitope prediction tool for protein-based antigens?
Many thanks in advance!
Julen
Dear julen
I have used and am currently using these tools to predict CD8 T cell epitopes prediction:
1- IEDB at
http://tools.iedb.org/mhci/
2- SYFPEITHI at
http://www.syfpeithi.de/
3- ProPred-I at
https://webs.iiitd.edu.in/raghava/propred1/index.html
I suggest to use them all and find the shared epitopes predicted by tow or all three tools using IEDB cluster tool (http://tools.iedb.org/cluster/).
You can see examples in my articles:
https://doi.org/10.1016/j.meegid.2019.103953
https://doi.org/10.1080/07391102.2020.1810126
Hope it will be useful
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