If you have several hundred cancer cell types, you have a rich resource for comparative analysis and experimentation. What experiments (innovative) would you do? Any thoughts are greatly appreciated!
Search PubMed for “pan-cancer” review articles; here are some publications to start with:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025898/
https://pubmed.ncbi.nlm.nih.gov/35121865/
https://pubmed.ncbi.nlm.nih.gov/37582357/
https://pubmed.ncbi.nlm.nih.gov/35705807/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349233/
Here's what you could do:
- Drug Discovery: Test drugs on various cells to find effective treatments and understand resistance.
- Cancer Biology: Compare cell types to understand what makes cancers unique and identify key pathways for targeting.
- Personalized Medicine: Develop models to test personalized treatments based on a patient's specific cancer cells.
This research can lead to more effective treatments and a deeper understanding of cancer as a whole.
Thank you Sabine and Sandeep for your inputs. These tasks have already been completed by several groups. Considering the wide audience, I was anticipating something innovative.
Find a shared/common or unique pathway shared by cancer cells and create an atlas for drug discovery
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