I am trying to separate 6-aminopenicillanic acid (6-APA) from phenyl acetic acid (PAA) and residual penicillin G (PG), the intention being to use the 6-APA in the production of amoxicillin. I have managed to separate the remaining components using 1,2-dichloroethane (DCE) as a solvent with an extractant and recover the DCE using Na2CO3 which I believe forms the 6-APA salt, moving it to the aqueous phase.

However I am left with the issue of recovering the 6APA. My initial intentions were to add HCl leaving 6-APA and NaCl but I am unable to find a method that would recover the 6-APA without requiring another separation from a solvent. 

Any help on this or an alternate method would be greatly appreciated.

My specification is I must have an exiting stream of 6-APA in water with minimal (negligible) impurities. The process must be continuous and as current I am adapting my method from the 2002 paper "Fractionation of the mixture obtained by the enzymatic hydrolysis of penicillin G" by D. Cascaval et al. The paper is included in this question

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