Can anyone assist with running the Linkage Analysis Tool 'Easylinkage' or any alternative tool for conducting linkage analysis and calculating LOD scores?
Linkage analysis is a method used to map genetic loci associated with specific traits or diseases within families. It helps identify regions of the genome that may contain genetic variants contributing to the trait of interest. There are several software tools commonly used for linkage analysis, such as:
1. MERLIN (Multipoint Engine for Rapid Likelihood Inference):
2. Allegro:
3. GeneHunter:
4. SOLAR (Sequential Oligogenic Linkage Analysis Routines):
5. PLINK (PLatform for INtegrated Knowledge):
These are just a few examples of the linkage analysis tools available. The choice of tool depends on the specific requirements of your study, the type of genetic data you have, and the analysis methods you intend to use.