I am doing research on learning and memory activity in rats. I have bought piracetam injection which is used for IM and IV route in human but I want to give through IP route in rats. can I do this?
Have you tried a literature search? I suggest trying the advanced search on Pubmed. For example, (piracetam[Title/Abstract]) AND intraperitoneal[Text Word] should give you some answers.
I think the injection which is available commercially would not be a decent experimental drug to test in animals because of the presence of other compounds in it.
Best thing to do would be buy the pure drug from a good company like sigma and reconstitute it with normal saline or whatever vehicle instructed to inject it intraperitoneally to the rats. This would be a proper way to study the effect of a particular drug.
Some of the nootropics have also used per oral in animal studies.
You should go through studies in the PubMed and then decide.
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