Can we synthesize Diacyl hydrazine from ester and acylhydrazine?

11 September 2024 1 7K Report

I want to synthesize diacyl hydrazine using cyclic drug (1) ester and cyclic drug (2) hydrazide via hydrazonolysis reaction. I have yet to decide on the selection of drugs. However, I cannot find previous literature on synthesis of diacyl hydrazine using ester and a hydrazide. Instead, the literature states reaction of acyl hydrazides with carboxylic acid or acyl halides group for the synthesis of diacyl hydrazine. Can we carry out the synthesis using ester practically. Under what condition can we carry out the experiment?

Ako Kaky

Not sure but did you check mannich reaction?

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