Can we include RCTs of a drug derivative in the meta-analysis?

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Gordon L Warren

It is up to you. You determine the research question and the study inclusion/exclusion criteria for the systematic review. Remember, for whatever you decide, you must be able to justify it. Think "would an expert agree with your decision?".

Amirhossein Hessami

That is compeletly right, but since the derivative have only one RCT! It will be logical not to include into meta-analysis