We have an orthotopic thyroid system to inoculate thyroid tumor cell lines in mouse thyroid using nude mice. Reference is attached. Tumorigenic papillary cell lines are TPC-1, K2 and BCPAP. Several anaplastic thyroid cell lines Hth83 and 8505C are also tumorigenic. References attached.
I've some suggestion, but its better than you consult with one of my previous supervisers (dr amir akhlaghi, shiraz univesity, shiraz, Iran) who did some researches in thyroid hormones.
There are many animal models for studying on abnormal thyroid functions. If you want to see it in murine models, you will be able to find some and get through the Charles river of Jackson Institute. It is depend on what is your subject to do. Tateki Kikuchi