Can someone suggest an appropriate neuronal cell line for studying the amyloid mediated neurotoxicity?

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Aseem Mishra

PC-12 is usually used. There are many other you can consider. Visit ATCC to find a suitable neuronal cell line.

Jogender Singh

Hi Jay,

People use several neuronal cell lines for studying the toxicity of amyloid aggregates. The most frequently used cell lines are PC12 and SH-SY5Y.

But I think for checking toxicity you can also use cell lines other than neuronal cell lines such as: HEK-293, CHO.

Best,

Jogender

Jay Kant Yadav

Dear Jogender, Many thanks for your support.

Dear Aseem, Many thanks for the information.