Blood glucose testing is an integral test to measure glucose homeostasis in the body. It is commonly used both for screening and diagnosis of diabetes. In addition, serial blood glucose testing, also called "self monitoring of blood glucose (SMBG)" is a common tool performed by patients with diabetes for the assessment of their glycaemic status. However, blood glucose testing represents an unpleasant experience for many people. Can salivary glucose be used as an effective alternative to blood glucose testing for screening, diagnosis and follow-up of diabetes?
Several studies have indicated the significant correlation of salivary glucose with blood glucose readings, and thus to the possibility of its use as a potential alternative to blood glucose measurement in the screening, diagnosis and follow-up of diabetes. The following article may be helpful in this regard.
Article Correlation of salivary glucose level with blood glucose lev...
The following article may be also useful:
Article Salivary glucose levels in diabetes mellitus patients: A cas...
Also, the following article may be helpful in this regard:
Article Evaluation of Parotid Salivary Glucose Level for Clinical Di...
Hi Dr Salman K. Ajlan . Yes it is a new recent technique. The Saliva Glucose Biosensor is the first non-invasive, saliva-based glucose test for diabetes management that measures glucose in saliva, not blood. See the link: https://gbs.inc/saliva-glucose/
See the following link: https://www.hindawi.com/journals/bmri/2017/2569707/
Also see the following link: https://www.mdpi.com/2075-4418/11/3/453/htm
Kindly see also the following link: Article Saliva: A tool in assessing glucose levels in Diabetes Mellitus
Based on the following RG link it has been concluded that salivary glucose is comparable to blood glucose in diagnosing and monitoring T2DM and is considered more advantageous than blood due to its non-invasive nature:
Article Salivary glucose as a non-invasive biomarker of type 2 diabe...
Kindly check the following RG link:
Salivary glucose estimation: A noninvasive method:
Article Salivary glucose estimation: A noninvasive method
Also, kindly check:
A non-invasive way of monitoring diabetes:
https://www.sciencedaily.com/releases/2020/04/200416135954.htm
Yes dear Dr Aref Wazwaz salivary glucose measurement is a non-invasive tool for glucose monitoring. It can be a promising alternative to blood glucose testing. Many thanks for your valuable contribution and also for sharing valuable links. My sincere gratitude.
Dear Dr Manal Hadi Kanaan. Indeed the non-invasiveness of salivary glucose testing and its comparability with blood glucose determination make salivary glucose measurement a potentially useful alternative for the assessment of glucose homeostasis and for screening and diagnosis of diabetes instead of routine blood glucose testing. Many thanks for your kind contribution and also for sharing useful links to enrich this discussion. My sincere gratitude.
Dear Dr بيداء عبد السلام مهدي Many thanks for your kind contribution and reply. My sincere gratitude.
Dear Dr Jose Risomar Sousa Thanks a lot for your kind contribution and reply. My sincere gratitude.
You are most welcome dear
Dr Salman K. Ajlan .
Wish you the best always.
Dear Dr Aref Wazwaz. We are so grateful for your kind participation and valuable replies. I wish you all the best. Kind regards.
Of Course, to avoid a painful and non-invasive procedure, a glucose-detecting-biosensor can be employed as a point of self-screening, indicated for the management of diabetes which will serve as a non-adjunctive approach to blood glucose testing for decisions regarding the management of diabetes.
Best wishes
Dear ميسم شهاب. Many thanks for your kind contribution and reply. Best regards.
Dear Dr Ismail Bamidele Afolabi. Many thanks for your kind contribution and valuable reply. My sincere gratitude.
Indeed the non-invasiveness of salivary glucose testing and its comparability with blood glucose determination make salivary glucose measurement a potentially useful alternative for the assessment of glucose homeostasis and for screening and diagnosis of diabetes instead of routine blood glucose testing.
Dear Enas Tariq Khudair Many thanks for your kind contribution and reply. My sincere gratitude.
Dear Dr. Radoslaw Walkowiak. Many thanks for your kind contribution and valuable reply with regard to salivary glucose testing. My sincere gratitude.
Dear Dr. salman...
really it is an important subject to investigate, there are many articles about this subject and they found a high statistical significant correlation between fasting saliva glucose and fasting blood glucose. so i think it can be applied as an alternative.
Dear Dr. Obay Abdulaziz. Many thanks indeed for your kind contribution and valuable reply. My sincere gratitude.
Dear Dr Salman Ajlan,
Of course, salivary glucose can be used for the diagnosis of diabetes and I invite you to read this article:
Article Effectiveness of Salivary Glucose in Diagnosing Gestational ...
Best regards,
Pr Hambaba
Dear Dr Leila Hambaba. Thank you so much for your kind contribution and valuable reply. Many thanks too for the attached article that enriched the discussion. My sincere gratitude.
Thank you Dr.Salman for this question.
Many articles study the salivery glucose level & correlate it to blood glucose testing & recommend it as alternative.
Here the attached link with one of this article.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763852/.
Dear Dr. Ruqaya Adnan Salih Thank you so much for your kind contribution and valuable reply. Many thanks too for the attached link that enriched the discussion. Best regards.
Dear Dr د. ابراهيم سلمان الموسوي There are several studies that have pointed to promising alternative role of salivary glucose instead of blood glucose both for screening of diabetes and also for monitoring of glycaemic status in patients with diabetes.
Kindly see the following links: best regards.
Article Salivary Glucose as a Diagnostic Marker for Diabetes Mellitus
Article Salivary glucose as a non-invasive biomarker of type 2 diabe...
Article Correlation of salivary glucose level with blood glucose lev...
Article Salivary glucose levels in diabetes mellitus patients: A cas...
Article Salivary glucose as a diagnostic tool in Type II diabetes me...
Dear Dr Alejandro Rodriguez-Garcia. Many thanks for your kind contribution and comment. My sincere gratitude.
Dear Dr بيداء عبد السلام مهدي In fact, numerous reports have highlighted the possibility of using salivary glucose both for screening of diabetes and also for monitoring of the glycaemic status in patients with diabetes. Please see the following links: Kind regards.
Article Salivary Glucose as a Diagnostic Marker for Diabetes Mellitus
Article Salivary glucose levels in diabetes mellitus patients: A cas...
yes
see this article
Article Effect of Diabetes Mellitus Type 2 on Salivary Glucose - A S...
Dear Dr Nooralhuda Alfatlawi Really many thanks for sharing this valuable link to enrich the discussion. My sincere gratitude.
Saliva sampling is easy, safe, and noninvasive and can be compared to blood in screening and monitoring GDM. Hence, salivary glucose can be a reliable alternative to blood glucose levels in gestational diabetic patients similar to type 1 and type 2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8525816/
Check https://gbs.inc/saliva-glucose/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203925/
Dear Dr. Chinaza Godswill Awuchi. Many thanks indeed for your valuable reply and also for sharing valuable links that greatly enriched the discussion. My sincere gratitude.
Kindly check this paper
https://www.sciencedaily.com/releases/2018/07/180723142935.htm
Dear Dr. Kiprotich Kiptum Many thanks for your kind contribution and sharing link. My sincere gratitude.
Dear Dr Ruqaya Adnan Salih. Really I'm grateful for your valuable participation in this discussion. I wish you all the best. Kind regards.
Other than salivary glucose, no other parameters in saliva were found to be markedly affected in diabetes mellitus. Therefore, salivary glucose can be utilized as an alternative diagnostic method for diabetes and as a general screen for prediabetes and undiagnosed diabetes.
The Saliva Glucose Biosensor is the first non-invasive, saliva-based glucose test for diabetes management that measures glucose in saliva, not blood.
Ganesan et al. (2021): reached the following results:
"Saliva sampling is easy, safe, and noninvasive and can be compared to blood in screening and monitoring GDM. Hence, salivary glucose can be a reliable alternative to blood glucose levels in gestational diabetic patients similar to type 1 and type 2."
Tiongco et al. (2018) found:
"Results
Using Pearson’s correlation and linear regression, a high degree and significant correlation was observed between blood and salivary glucose (r = 0.715, p
Dear Dr Chuck A Arize. Thank you so much for your valuable participation to this discussion. My sincere gratitude.
Dear Dr Sundus F Hantoosh. Many thanks for your kind contribution and valuable comment that enriched this discussion. Best regards.
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