Metabolic disorders are only controlled but not completely cured from the Scientific perspective

Yes, gout is considered a metabolic disease. It is a type of arthritis that results from the buildup of uric acid in the body, typically due to the body's inability to process or excrete it properly. This condition is often associated with metabolic factors such as diet, obesity, and genetics.

The metabolic cause of gout is primarily due to deficiency or alteration in the enzyme called xanthine oxidase. Xanthine oxidase is responsible for catalyzing the conversion of hypoxanthine and xanthine to uric acid as part of the purine degradation pathway. This enzyme plays a critical role in the final step of purine metabolism, leading to the production of uric acid. An excess of uric acid in the body, often due to factors such as diet, genetics, or kidney function, can contribute to conditions like gout, where uric acid crystals can accumulate in joints, leading to pain and inflammation. Drugs like allopurinol like allopurinol can be used to treat gout. Allopurinol is a medication commonly used in the treatment of conditions like gout and hyperuricemia (high levels of uric acid in the blood). It works by inhibiting the enzyme xanthine oxidase, which is involved in the production of uric acid. By reducing the activity of xanthine oxidase, allopurinol helps lower uric acid levels in the body. This, in turn, can prevent gout attacks and reduce the risk of uric acid crystal formation in joints and other tissues. Allopurinol is typically taken orally as a prescription medication and is considered a long-term treatment for managing conditions related to excessive uric acid production.