Can I use syngeneic mice model to study the role of CAF ? I have gonr through recent papers related to this and found most of the papers are worked with Balb/c nude mice with xenograft. Is it valid to do the experiment with syngeneic model (ID8 in C57BL/6) ? And also, please suggest if Intraperitoneal tumor formation is good to isolate fibroblast from the tumor ?