Can I use discovery studio for simulating a compound docked with a human protein target using Glide-IFD docking?

More Dr.Sri Lavvanya Priya S Prakash's questions See All

MODELLER DOUBTS

Hi all , I installed modeller9v8 in my PC. the command page opens. but when i type as " sequence.ali", i get the following command: " 'sequence.ali' is not recognised as an internal or external...

02 March 2011 1,688 5 View

Kindly help

I am asked to look for sequence similarity and identity for a target protein which is of 120 amino acids. But I have to compare this target with a database of 1500 sequences. so i do not know...

01 February 2011 5,421 2 View

overlaps

I have a sequence of 100 amino acids. I want to see the overlapping segments in the sequence by splitting into dipeptides, tripeptides. so how to do this analysis? is there any online tool to do...

01 February 2011 7,225 2 View

suggestions please

I am asked to look for sequence similarity and identity for a target protein which is of 120 amino acids. But I have to compare this target with a database of 1500 sequences. so i do not know...

01 February 2011 9,303 2 View

RMSD & TM

Hi all, When I work with online servers for my protein, i get an RMSD value of -1 and TM score of -1. What does these values suggest of my protein? can any one of you...

31 December 2010 7,105 2 View

FASTA

Hi, I have a sequence ( human -target)) of 600 aminoacids long. (No structure is available.). similarly i found a sequence(template) in monkey which is the same 600 amino acids long. when both...

11 December 2010 7,049 1 View

OBEJCTIVE TYPE BIOINFORMATICS BOOK- FIRST OF ITS KIND

Hi all I have published a book on 'OBJECTIVE TYPE BIOINFORMATICS" very useful for students who study for various entrance examinations. The cost of the book is Rs.200. 5% discount can be given....

11 December 2010 2,181 1 View

rosetta

Hi can anyone teach me how to work on ROSETTA 3.1? my mail : [email protected]. please send me the steps to work with rosetta

11 December 2010 5,810 1 View

How can I prepare virus for a TEM or SEM imaging?

I have virus (viral hemorrhagic septicemia virus) in suspension and the experiment will not involve cells. What level of TCID50 is preferred?

11 August 2024 3,115 1 View

Handling Missing Data and Building a Predictive Model with Incomplete Information ?

I am developing a predictive model for a water supply network that involves 20 influencing points. However, I only have historical data for 10 out of these 20 points. I would like to know how to...

10 August 2024 4,005 2 View

Which Scopus Journal provides the most affordable fees?

"PUBLISHING IN A SCOPUS JOURNAL" Researchers are now at a cross road. The critical need to publish in a Scopus or ISI, etc journal is ever vital. Journal Publication fees must be submitted....

10 August 2024 8,621 1 View

Seeking Advice on Viability and Execution of Undergraduate Thesis Topic?

Hello everyone, I am currently developing a thesis proposal and would appreciate your input on its viability and how to effectively carry it out. My proposed topic is: "Does the perceived threat...

10 August 2024 8,992 0 View

Is it possible to use the Fused Deposition Modeling (FDM) to additively manufacture interconnected porous structure generation of >100-200 micrometer?

Usually, additive manufacturing techniques like SEBM, SLS, and SLM are used for interconnected porous lattice structure generation with sizes of >100–200 micrometers. Can the Fused Deposition...

09 August 2024 7,892 0 View

How to define an anisotropic material with asymmetric elastic compliance/stiffness matrix in ANSYS APDL?

I need to model an anisotropic material in which the Poisson's ratio ν_12 ≠ ν_21 and so on. Therefore, the elastic compliance matrix wouldn't be a symmetric one. In ANSYS APDL, for TB,ANEL...

09 August 2024 5,048 2 View

Who will be moral responsible for the death of thousands of people in the event of an earthquake?

Who will bear moral responsibility for the deaths of thousands of people in the event of an earthquake? Weeks and months remain before the onset of strong earthquakes that bring death to...

08 August 2024 6,134 12 View

How can I apply boundary conditions in an orthotropic steel deck numerical model using ABAQUS software?

I am trying to simulate vehicular loading on an orthotopic steel deck bridge section in ABAQUS software. The red arrow mark in the attached figure indicates the direction in which the vehicle will...

08 August 2024 719 0 View

Can you suggest reliable sources defining "3D mesh" and "3D city models"?

Dear fellow researchers, I am currently working on a paper where I need to provide a reliable reference that defines and distinguishes between 3D mesh models and 3D city models. Although I am...

06 August 2024 9,986 2 View

Are there any instruments for studying time similar to the way it is in space?

There are a huge number of methods for studying objects in space, according to the senses (and not only). Mechanical, thermal, optical, acoustic, electrical, magnetic, based on particle beams,...

06 August 2024 7,102 0 View