Although I know that ESC are highly proliferative cell types, I just want to know if one can arrest them in G0 phase? Thanks!
Yes, I think This affect their pluripotency.......
Take a look at this paper!
http://www.sciencedirect.com/science/article/pii/S0006291X0501096X
Pluripotent stem cells are by definition capable of indefinite growth and proliferation. So, any maneuver that interferes with a continuous cell cycle may affect pluripotency of the cells.
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