Javan; here's an article that may be helpful with the question you posed.
CCR5 belongs to a large family of chemokine receptors that are expressed on surface of lymphocytes and other cell types, where they are involved in signaling and coordination of immune responses. Similarly to CXCR4, CCR5 is also an HIV co-receptor. CCR5 and other chemokine receptors belong to an even larger family of seven transmembrane proteins coupled to G proteins, a very important family that includes many signaling receptors, such as rhodopsin and beta-adrenergic receptors. Seven transmembrane receptors are large molecules however, their three-dimensional structures are still poorly elucidated from physico-chemical spectroscopic methods, such as X-ray crystallography. Only the structure of rhodopsin, the two beta adrenergic receptors, and the adenosine receptor have been recently characterized. The approximate structures of other receptors, such as CCR5, have been modeled based on similarities revealed by the structures of these related proteins.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185609/
As has been answered by Bell, as of now complete characterization of the CCR5 chemokine has not been elucidated. This chemokine came into prominence during the height of the HIV pandemic. Induction of this mutation into a neonate might not offer major survival advantage. The question of hetero and homozygosity shall still persist. Only homozygous mutations offer resistance to HIV infection.
Dear sir/Madam
See these links may be useful for you.
1) Association of CCR5-delta32 mutation with reduced risk of ...
www.ncbi.nlm.nih.gov/pubmed/18972295
Traduire cette page de V Berce - 2008 - Cité 12 fois - Autres articles
Association of CCR5-delta32 mutation with reduced risk of nonatopic asthma in Slovenian children. Berce V(1), Repnik K, Potocnik U. Author information:
2) A130: Is the CCR5-delta32 Mutation Protective Against ...
www.ncbi.nlm.nih.gov/pubmed/24677884
Traduire cette page de V Chasnyk - 2014
The purposes of the study was to compare the prevalence of the CCR5-delta32 mutation in children with and without soJIA, to assess the association of this ...
3) Chemokine receptor CCR2 and CCR5 ... - NCBI
www.ncbi.nlm.nih.gov/pubmed/10400139
Traduire cette page de C Szalai - 1999 - Cité 64 fois - Autres articles
Chemokine receptor CCR2 and CCR5 polymorphisms in children with ... A common 32-bp deletion mutation in the CCR5 gene (CCR5delta32) and a G-to-A ...