Well, what are you interested in?  My advisors often had ideas for side projects related to theirs that they would suggest.

Opting for clinical microbiology research would be good for medical students like you. There have been ample of studies on Pathogens( bad bugs) so maybe you can research about good bugs like probiotic LAB, their isolation, characterization and assessment of their antimicrobial activity.

Since you are student, you have think about many aspects:

what kind of infrastructure is available to you? How much of time you will need to carry out the project? How much time you can devote towards bench work. If you end up with positive answers, you have many choices. Starting from clinical microbiology to medical bioiformatics, metagenomics as well as NGS based transcriptomics studies. But there few problems whoch may be of help to India. As an Indian I feel you can start to think about these. May be in future when you mature and become a doctor cum resercher you will find solution to any one of these:

1. Dengu virus: It is a growing threat to population inhabiting Indian subcontinent. Although, to work with that virus, you need to have good infrastructure and knowledge, you can start with simple bioinformatics work with genome mining, comparative genomics coupled with thorough following up of all the literatures (based on both wet and dry lab experiments) pertaining to it as well as to those viruses, that are close to it. If you starat, you will find its an ocean, may be you will get some real questions to following through your entire life (even after your project, may be afterwards when you mature into a good doctor cum researcher). 

2. Another aspect is we Indian have huge diversity as far as food habits are concerned, I feel there is a strong correlation between the food that a particular region eats upon and distinct gut microflora. You have start looking at this corelation through hypothesis and questions (there are actually many questions you can ask: for example: is there any dominance of particular group(s) of prokaryote(s) associated with particular food?  Is the population has bias towards some special disease (may be you can target gall bladder stone etc), like that. This is also an ever ending work But if you start you will think and get into depth and as i have already mentioned may be in coming 20-25 years will will have some solution. You can simply start by collecting gall stone from OT to microbiology laboratory, doing culture dependent and independent through analyses of its microflora with suitable control from healthy individual (remember there will be many factors for your experiments such as age, sex, etc other than food habbit). This work will need through survey, inventory of database (case to case patient history, if possible genetic background) etc. You have huge advantage as for sampling you do not have to go anywhere.

3. Role of bio film forming bacteria (esspecially the Enterococci group) and their status as emerging MDR properties in indian population. I think this aspect is new but you know Enteroccci are now getting detected from various niches (both natural, manmade etc). I feel In India this will be a problem in future.

$. There are few more diseases that is killing our heaven: like malaria, tuberculosis etc. But many groups are working on that and for Mycobacterium tuberculosis work, P3/BSL3 infrastructure is advsable.

You also think, Think from the core, you will get/know about many diseases that are currently in the state of infancy.

All the very best.

Thanks all for ur help...... I am interested in anti microbial resistance

There are a lot of recently published papers on the molecular-level mechanisms of anti-microbial resistence. You may search and read first.

http://www.nature.com/nature/journal/v517/n7535/full/nature14098.html

Dr. Singh is asking you the correct questions that you need to answer first.  Then you can answer these questions:

1. Does your school have equipment for elaborate study (biochemical, microbiome, genetic analysis)? 

2.  Is this a short term study or is this a long term more complex study? 

3.  Do you prefer using cultures to study questions such as prevalence of types of bacteria and their antibiotic resistance or pick an organism and study how much resistance it shows in comparative groups?

4.  A lot of work in India is focused on the antibacterial activity of various plant extracts, and still much to do.

5.  An interesting project to me (from across the seas) would be to compare a selected species of bacteria in the mouths of betel or betel nut chewers to non-chewers to see which mouths have higher percentage of antibiotic resistant bacteria.

Good luck in your studies.  I hope to get to India for some collaborative research in the next year or two (looking for collaborators to begin work on the projects and obtaining funding).

Try to keep it simple, read around the organisms you are interested in and ask small questions - it will grow from there.  

Good luck

Well you mentioned about your interest in microbial resistance so i think you should do research on Rapid detection of multidrug-resistant Mycobacterium tuberculosis by multiplex allele-specific polymerase chain reaction. The mechanism of ARMS PCR is quite popular and trending for the detection of microbial resistance. Also isolation of plasmid from the resistance bacteria and analysing it could be the prospects for development of different drugs.

I hope this will help.

https://www.researchgate.net/publication/256084505_Development_of_a_single_multiplex_amplification_refractory_mutation_system_PCR_for_the_detection_of_rifampin-resistant_M_tuberculosis

Article Development of a single multiplex amplification refractory m...

Getting a research topic is simple, get from within your community, school or health facilities, Ask your self a question, for example how often do we wash hands? Does this act really helps us stay free from bacteria. then u can investigate this and finally it forms research project. you may also search about Pseudomonas putida: a plant pathogen that secretes an ice-nucleating protein, responsible for the formation of ice crystals. Strains of this organism are commercially used at ski resorts to create finer crystals in snow-making machines.

You can research on antimicrobial susceptibility patterns of important clinical pathogens obtained from hospitals in your area.

microbiota and MDR these two topic are hot in medical microbiology

Microbiota