If the plant extract is dissolved in ethanol only means how can i administer the plant extract to the albino rats?

crude plant extract is dissolved in ethanol. But ethanol is not consumable. Is there any other way to administer the drugs to the rats.

04 May 2018 9,038 11 View

How do i prepare the plant sample for NMR analysis?

I have a crude extract of the plant powder. I need to do NMR analysis. How can i prepare the pure sample for NMR analysis from crude extract?

03 April 2018 1,956 8 View

What are the chemical solution to dissolve the crude extract?

I used benzene as a solvent to extract the plant powder? I used water, 100% DMSO, 5 and 10% Tween 80, 5 and 10% Tween 20, ethanol, methanol. But the extract does not dissolved. other than these...

03 April 2018 9,325 3 View

Where do i get the HaCat cell lines?

I need a HaCat - Human keratinocytes cell line for my research work. I need to know the availability of the cells.

03 April 2018 9,262 3 View

Can i use 5% tween 80 to dissolve plant extract (benzene used as solvent)?

Benzene extract of the plant does not dissolve in water.

03 April 2018 1,057 6 View

Is it necessary to test the toxic effect of the biosynthesized nanoparticles, even after the plant extract has been proven that has no toxic effect?

To test the toxic effect of of the silver nanoparticle synthesized using plant extract. But the crude extract of the plant had no toxic effect.

02 March 2018 9,019 9 View

No title

I am not aware about the UV lamp model to induce psoriasis in the laboratory rats. Is this lamp is OK to induce psoriasis?

07 August 2017 7,720 3 View

How do i identify the nature of the compound?

I had the compounds list of the plant extract, obtained through the GC-MS analysis. How do i identify whether the compounds are new or already identified compounds?

05 June 2015 2,614 0 View

What are the cell lines (which is best) to study antidiabetic activity?

I want to study the antidiabetic activity in vitro. What are the cell lines other than pancreas are the best to study the antidiabetic activity? And in the pancreas which cell line is best to give...

03 April 2015 5,221 9 View

It is possible to extract the fractions in the plant crude extract through HPLC analysis without going GCMS?

03 April 2015 3,111 4 View

Is there any test to determine the cardiovascular risk of patients with obesity? from the perspective of obesity?

We found tests to determine cardiovascular risk taking into account lipid profile, blood pressure, age, history of diabetes, other laboratories. But when weight is involved, there is a paradox. I...

02 March 2021 6,036 1 View

Do I need to introduce HFD to ob/ob mice to obtain a T2DM model?

I am planning to work on T2 diabetic animals and check the efficacy of probiotics. My initial plan is to fed B6 animals with HFD for a while. But now, I have the chance to work on ob/ob mice. My...

18 February 2021 6,896 3 View

How seniors face covid 19 without fear?

Seniors in the world with diabetics and hypertension and heart diseases are millions ,and they are facing covid.therefore we should give them advices and precausions to face covid 19,this...

26 January 2021 8,349 4 View

What is role of chronopharmacology or circadian rhythms in metabolic diseases including obesity, diabetes and cardiovascular diseases?

Chronopharmacology is branch of biological science which deals with daily life, sleep and wake, day and night, feeding and fasting and other effects. we can manage many diseases including...

18 January 2021 9,045 3 View

What type of interventional study is this?

Hi, I'm evaluating some medical papers to write a review, but I'm having trouble defining the study design of the following paper: Neurophysiological recovery after carpal tunnel release in...

04 January 2021 1,571 4 View

Diabetic patients and religiosity?

How to convince a poorly educated diabetic patient, of high religiosity, who believes that complications will definitely occur with the will of the God however he does

29 December 2020 2,304 4 View

Are the same rapid and clinical test of diabetics?

Are the same rapid and clinical test of diabetics?

28 December 2020 9,109 12 View

What are the Methods to evaluate nephroprotective activity of herb in diabetic and hypeetensive nephropathy or CKD?

Usualy nephroprotective drugs of plants orgin were evaluted in nephrotoxicity animal model. But CKD secondary to HTN and DM is also common. What are the method to develop these animal model in a...

28 December 2020 161 2 View

Are COVID 19 vaccines reliable for people with medical conditions, like those with respiratory issues, diabetes, heart problems, etc.?

Are COVID 19 vaccines reliable for people with medical conditions, like those with respiratory issues, diabetes, heart problems, etc.?

22 December 2020 5,948 7 View

Is it possible to calculate the sample size of a clinical trial with the Cohen formula when there is no similar article?

We are trying to design a clinical trial on type 2 diabetes patients. The main data that we want to assess include FBS, 2hpp, HbA1c, insulin, and HOMA-IR. Also, we will assess the lipid profile...

21 December 2020 2,454 3 View