X-ray diffraction is not very efficient for hydrogen bond studies. So try neutron diffraction if you have larger crystals (at least of mm size). Surely chemical knowledge combined with X-ray data can help but that is an indirect method. By measure neutron diffraction intensities you can determine the proton positions directly and accurately. If you do not have too many H atoms then you do not have to deuterate the sample even.
There are several well-known geometrical criteria to characterise hydrogen bonds, but you probably need to be a little more specific to get a useful answer to your question. What you most likely want to start by looking at is the D...A distance, as well as the D-H...A angle, but that just get you started.
If to quantify H-bond, you mean to find/list each H-bond occurs in the structure, there is a plethora of software that can be help you with this task. I recommend the package PLATON by Ton Spek (http://www.chem.gla.ac.uk/~louis/software/platon/). The option “Calc H-bond” in GEOM-CALC menu analyzes the D...A and H…A distances, as well as the D-H...A angles, and can identify the type of H-bonds occur in the structure. Alternatively, you can use the Mercury program (http://www.ccdc.cam.ac.uk/Solutions/CSDSystem/Pages/Mercury.aspx), a crystal structure Visualizer, which can explore and analysis the short contacts taking pace in the crystal packing. You can easily identify the H-bond by yourself.
If to quantify, you mean to estimate the ‘strength’ of H-bonds involved in the structure, maybe a bond valence analysis can be useful. In this case, I could suggest the software Valist (http://www.ccp14.ac.uk/solution/bond_valence/).
X-ray diffraction is not very efficient for hydrogen bond studies. So try neutron diffraction if you have larger crystals (at least of mm size). Surely chemical knowledge combined with X-ray data can help but that is an indirect method. By measure neutron diffraction intensities you can determine the proton positions directly and accurately. If you do not have too many H atoms then you do not have to deuterate the sample even.
Here's the tutorial in JANA2006. By using electron density map the Hydrogen atoms can be add to the structure. Here is the result for (NH3-CH2-CH2-NH3)2.ZnCl6.
Bond-valence analysis might also come in handy, depending on what kind of compound the structure is presented for. One of the most common example is locating hydroxyl group and distinguishing from terminal oxygen =O or fluoride -F in inorganic compounds. Not applicable to organic molecules though.