I want to know the inhibitor for mannose phasphotransferase system(MPT) which is the main sugar transporter system in Gram positive bacteria.
doxorubicin and Mannose-binding lectin are potent inhibitors of MPT system. Mannose-binding lectin (MBL), a mammalian lectin, is a pattern recognition molecule of the innate immune system and recognizes carbo-hydrates that are exposed on pathogens.
This is not difficult; the same inhibitors used for glucose phosphotransferase can be used here too.
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