Can anyone share some articles on In silico drug design ?

Hi Hasan,

I am attaching some for your reference

DiMasi JA, Hansen RW, Grabowsk HG (2003) The price of innovation: new

estimates of drug development costs. J Health Econ 22:151–185

Ekins S, Mestres J, Testa B (2007) In silico pharmacology of drug discovery:

methods of virtual ligand screening and profiling. Br J Pharmacol 152

(1):9–20

Graupner M, Gutkin B (2009) Modeling nicotinic neuromodulation from global

functional and network levels to nAChR based mechanisms. Acta Pharmacol

Sin 30:681–693

Hansch C, Fujita T (1964) Rho-sigma-pi analysis. A method for the

correlation of biological activity and chemical structure. J Am Chem

Soc 86:1616–1626

Jones RS, Woodhall GL (2005) Background synaptic activity in rat entorhinal

cortical neurones: differential control of transmitter release by presynaptic

receptors. J Physiol 562:107–120

Myers S, Baker A (2001) Drug discovery—an operating model for a new era. Nat

Biotechnol 19:727–730

Noori HR, Jäger W (2010) Neurochemical oscillations in the basal ganglia. Bull

Math Biol 72:133–147

Noori HR, Spanagel R, Hansson A (2012) Neurocircuitry for modeling drug effects.

Addict Biol 17(5):827–864

Noori HR (2012) The effects of the acute administration of low-dosage ethanol

on the phasic neurochemical oscillations of the basal ganglia. Math Med Biol

Oprea TI, Matter H (2004) Integrating virtual screening in lead discovery. Curr

Opin Chem Biol 8:349–358

O'Connor KA, Roth BL (2005) Finding new tricks for old drugs: an efficient route

for public sector drug discovery. Nat Rev Drug Discov 4:1005–1014

Paolini GV, Shapland RH, van Hoorn WP, Mason JS, Hopkins AL (2006) Global

mapping of pharmacological space. Nat Biotechnol 24:805–815