Any suggestions on the tripplet bands I observed at 72,56, and 45Kda for CSE/CTH protein in rat heart tissue?

Rat heart tissue, I am assaying for CSE/CTH protein expression always give a triplelt bands at 72,56 and 45Kda (Published data only showing a single band detected at 45Kda in heart tissue). The...

24 June 2020 4,811 3 View

How to Interpret Panel Regression Model with Low R squared and adjusted squared values?

I am dealing with panel data, n=28 and t=7. All the panel models including POLS, FD, FE, RE generate very low R squared values less than .10, but between variation model generated a r-squared of...

18 February 2020 3,336 3 View

Why is there no DNA after midiprep even though there was enough bacterial growth?

24 February 2015 4,179 9 View

How long and how could I best preserve gill tissue for histopathology?

I have a number of small bodied fishes that I want to extract gills from, so as to do morphological analayses and histopathology. The problem is: I have a lot more that I need to do the same work...

28 January 2021 6,091 3 View

Best loss function for special classification problem in neural networks ?

Hello, I've build a Conv1D model to classify items into 6 categories (from 0 to 5). (simplified example) I use therefore a CrossEntropy loss function that penalizes the errors with high...

19 January 2021 3,199 1 View

Is there any variation in d dimer levels due to the different methods adopted for analysis?

While doing my research work, I have noticed that the D- dimer levels of normal animals (dogs) are given in different ranges in different publications. Is there any variation occuring in d dimer...

08 November 2020 296 1 View

In this sterile needle biopsy wet-mount, does the motility pattern fit with Oomycete zoospores?

We are examining tissue from a cluster of human and canine patients with a similar pattern of systemic illness of unknown cause. All members of the cluster have evidence of motile zoospore-like...

23 October 2020 4,480 3 View

How to do scoring for fat droplets in Histopathological sections?

I want to do scoring for macrovesicles and microvesiclular fat diposits in Histopathological Liver sections. Can anyone suggest me a software and discuss a suitable protocol to achieve this. I...

18 October 2020 9,727 2 View

How can you prepare rats synovium of knee joint for histopathology, H and E and special stains?

Tissue processing techniques in particular..

06 September 2020 5,701 3 View

I have two H and E stained histopathology image datasets of breast. I wanted to use both for training a single algorithm. So how can i do this?

Should I combine both the datasets and train the ML algorithm or should I need to train the algorithm separately with the datasets and test on a single set.The test set is the combination of both...

08 May 2020 6,648 5 View

How sure are you, that after TUR-B for NMIBC, to have enough muscle tissue for correct histopathological examination?

Deep resection for correct histopathological analysis in TUR-B can be challenging for the surgeon with a low to mid-experience level. This leads to inadequate analysis, possibly postponing radical...

11 April 2020 5,713 3 View

Should I test for HWE in dataset of inbred animals without random mating?

Hi, I am doing a GWAS analysis of european bison's a dog's SNPs. Right now I am doing multiple data clean up, according to previous studies and what I have learned. I was thinking, if it is ok to...

18 March 2020 3,103 3 View

Seeking for expert in cytology and histopathology equipments?

Hello everyone, I am looking for a scientist who have experance in histopathology and cytology to advise me the essential equipments that using in Histopathology and cytology Laboratory. We want...

02 March 2020 8,217 4 View