I am interested in performing Fischer-esterification of COOH- terminated PEGylated gold nanoparticles and ethylene glycol, to study the self-assembly of nanoparticles. For this, I have managed to functionalize citrate capped gold nanoparticles with a mixture of SH-PEG and SH-PEG-COOH, in aqueous media. But, redispersing it in ethylene glycol by centrifugation or dialysis seems to be a bit challenging, as particles start to collapse.
Can anyone suggest me a trick to over come this situation?
Thanks in advance.