Can anyone explain me about Pharmacokinetic Adjustment (PK) in Acceptable Daily Exposure (ADE) calculation?

19 April 2017 1 4K Report

from where we can get the value of PK?

Depends upon the human variability and other factors that is determined by the expert toxicologist. There is no "cookie cutter approach." Go to https://goo.gl/dGrSqo for a large catalog of PDE/ADE monographs. BTW - you're not going to get this information for free. Occupational toxicologists expect to get paid and don't give away their expertise for free.

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