Can anyone discuss the claimed efficacy of COVID-19 vaccines (e.g., 80%, 95%, etc.) by different manufacturers (COVAX, Pfizer or others)?

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Bruce Lyday

The interim analyses of the Phase 3 results show that compared with the placebo group, the vaccine groups showed 90-95% fewer infections. These results are not definitive, but given the public health risk of COVID, the decision was made to approve the vaccines.

Giridara Gopal Parameswaran

The interim analysis use Bayesian approach and few assumptions on the posterior. It is possible to get higher VEs with assumptions that can drive the estimate to the higher end. On the other hand, to keep it simple. Even a 90% VE doesn't mean 90% of the population can be protected. It simply translates to the fact that if 100 infections are about to happen in a naive population, 90 of them would not happen if the population was vaccinated.

Arvind Singh

The following study clearly suggests that Pfizer (BNT162b2) COVID-19 vaccine is 94% effective in real world setting.

Article BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Mass Vaccinat...

The full-text of the article is available online.

Pfizer (BNT162b2) and Moderna (mRNA-1273) COVID-19 vaccines are 90% effective in real world conditions.

Article Interim Estimates of Vaccine Effectiveness of BNT162b2 and m...

Ari Happonen

Have you had time to study these already?

Why you can't compare Covid-19 vaccines

https://www.youtube.com/watch?v=K3odScka55A

Which COVID-19 vaccine is the best? | DW News

https://www.youtube.com/watch?v=BRKZh_RXJC0

Top 8 Vaccines for Covid-19 | Comparison

https://www.youtube.com/watch?v=m6DpETHsbQw