Can any one tell me the role of "GRK2-4KR" Mutation?

04 May 2016 1 1K Report

There are many mutations available for G-protein regulating Kinase 2 (GRK2), but I am not clear about the role of 4KR mutation. Anyone has idea regarding this?

Steffen Schüssler

Dear Srijan Acharya,

K to R may lead to a loss of the kinase function, as for GRK3-K220R.

all the best,

Steffen

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