I need original papers on Genetically modified products(successful or failed) example:Crops, Food products ,medicinal products.
Thank you.
I think you should specifiy this question as there are thousands of original articles on the subject
I think you should specifiy it as there are thousands of original article on the subject.
Hi Bhagya,
Here is the famous one-- the original paper (Science) of 'the first glowing plant' from genetic transformation of the firefly luciferase gene. You can see this 'glowing plant' picture all over in the Plant Biology textbooks. Companies have since developed Luciferase Assay Systems which can be used for reporter quantitation in mammalian, plant and bacterial cells.
Best,
Hi .....Aftab Ahmad.
Bt cotton, Insulin, Tomato, Golden rice, corn, papaya, squash, potato and vitamins etc.
Hi Bhagya,
This is another high-profile one (Science): the "Golden Rice" one. Are you writing an essay? I will send you more, if I come across more.
Best,
Hi Bhagya,
This is a GM breakthrough for cotton (PNAS). It is especially useful for industries for producing cottonseed oil and cottonseed meals from cotton seeds. Cotton seeds are used for producing several products including cottonseed oil and cottonseed meals (see attachment #1 and #2). Cottonseed oil is used in many food products for human consumption, while the by-product high-protein cottonseed meals are used for animal (such as cow) feeds. The problem is that the cotton seeds contains a toxic compound (pigment) called gossypol, which cotton plants used to protect themselves from insets. Gossypol locates in the glands in the seeds (see attachment #3). Generally, the factories have to remove the gossypol with a mechanical method before further process, and this costs money. So, cotton breeders have long being seeking an efficient molecular way to remove/eliminate the gossypol in the cotton seeds. This paper describes how researchers used RNAi technologies to remove the gossypol in cotton seeds by blocking the biosynthesis pathway of gossypol through genetic transformation. While eliminating gossypol in the seeds, the pigment is still kept in the aerial parts (such as leaves etc) to protect them from pests. I have worked on cotton gossypol genetic transformation for a while.
Paper: Engineering cottonseed for use in human nutrition by tissue-specific reduction of toxic gossypol
Hi Bhagya,
This is another famous case for transgenic breeding: transgenic Papaya: The use of virus coat protein (cp) to produce papaya ringspot virus (PRV)-resistant papaya. PRV has been a serious papaya disease in Hawaii. See attached (1) the original research paper (Nature Biotechnology). (2) the story/history of producing PRV-resistant papaya in Hawaii, (3) pictures of transgenic plants vs. non-transgenic plants.
Hi Bhagya,
This is yet another successful use of transgenesis in food industry- transgenic potato. This technique has patented: "Suppression of the Vacuolar Invertase Gene Prevents Cold-Induced Sweetening in Potato". After harvest, potatoes are cold-stored to prevent sprouting or disease loss. However, during cold storage, cold-induced sweetening occurs. The potato chips processed from these cold-stored potatoes become dark in color (see attached picture) and taste bitter. So, researchers tried to develop methods to silence this cold-induced sweetening gene (vacuolar Invertase gene). Potato chips processed from this cold-stored GM potato give light in color (see attached paper for detail).
Also attached an article:
The use of GM plants (Arabidopsis) to uncover landmines.
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