Can any one give me the reason s from uses anhudrous sodium actate instead of sodium acetate for cyclization thiosemicarbazide ?

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Chinaza Godswill Awuchi

Kindly check this link

https://www.tandfonline.com/doi/full/10.1080/17415993.2011.601869?src=recsys

http://www.sapub.org/global/showpaperpdf.aspx?doi=10.5923/j.ajoc.20160602.01

Sodium acetate (CH3COONa) is a solid-state salt that can not be used in anhydrous or liquid form as an acid or base. Now, with NaOH being a strong base and CH3COOH being a weak acid, the resulting solution is fundamental in nature. Sodium acetate is therefore essential in an aqueous medium.

https://byjus.com/chemistry/sodium-acetate/

Shaima Ibraheem Chyad Al-khazraji

Thank you doctor