Can an “errata corrige“ be published without mentioning the comment which asked for it?

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Is there an open source tool the measures the GRAVY index of a peptide incorporating the PTMs and unusual amino acids (e.g. hydroxyproline)?

Right now, I am using ProtParam to compute GRAVY index of peptides. However, some of my peptides are post-translationally modified, and contains unusual amino acids. I assume that ProtParam does...

29 January 2021 8,300 4 View

How long does the peptide cleavage cocktail last before it gets expired?

The cleavage cocktail is composed of Phenol/thioanisole/water/TFA/triisopropylsilane. I only prepare 10 mL cocktail per peptide but can the activity of the cocktail prepared at 100 mL last for a week?

10 January 2021 7,424 3 View

Could you recommend an inexpensive camera for a prototype DIC system?

I was thinking of choosing Raspberry pi HQ 12MP. and what software do you recommend. I am working on a measurement system for a plate with an area of approx. 500x500 mm2

30 December 2020 3,064 2 View

Is there an interpretation for Lineweaver-Burk plot which linear regression lines intersect themselves on quadrant I?

Lineweaver-Burk replots for enzyme inhibition prints regression lines intersecting themselves on quadrant I. The interpretations for competitive, noncompetitive, or uncompetitive inhibition does...

24 November 2020 7,753 3 View

Protein long term storage can have an effect in pH changes?

I have a long term stability study with a protein that as an isoletric point lower than the buffer (Tris buffer), and I am seeing a sustantial drift from the initial pH to 12 month point....

10 November 2020 4,445 3 View

When having a particular combination of two drugs in the same nanoparticle, how to discriminate between additive and synergistic anticancer activity?

Both additive and synergistic activities have been described for chemotherapy drug combinations co-loaded in the same nanoparticle. Such strategies have been aimed at cancer therapy via dual...

05 October 2020 5,027 5 View

How to crystallize curcumin from ethanolic turmeric extract?

I'm having difficulty recovering curcumin from my ethanolic extract. I tried reducing its solubility in the solution by slowly adding water, but the solid just crashed out of the solution in very...

03 September 2020 3,020 5 View

Incorrect FEM stress analysis with quadrilateral element... why?

Hi everyone, To put this in context, , I am making a Matlab algorithm for topology optimization that consider fatigue breaking. I am basing on the Ole Sigmund algorithm, which discretices the 2D...

11 August 2020 1,532 6 View

Could you please share some tips for writing a good literature review (in economics)?

For instance, lately, I've seen that many authors use a summary table with relevant papers.

19 July 2020 3,351 5 View

How to extract Google Earth high resolution DEM?

Recently, Google Earth introduced for the mexican scenes a high resolution DEM, which are very accurate in cities. Do you know a way to extract it legally?

29 June 2020 9,258 3 View

What are the values needed for gabor filter's parameter for cifar10 data?

Hi, I implemented a code to gabor filter cifar10 data but the images after being filtered and stacked are not clear like the original images. I think the problem is in the way I am using the...

03 March 2021 6,317 1 View

What techniques can I use to determine the miscibility of polymer blends?

The term miscibility refers to the single-phase state in thermodynamics. I do not mean the compatibility of different components. To determine the miscibility I know several techniques such as...

03 March 2021 4,107 4 View

New Journal, "Integrative Psychological and Behavioral Science" -- do you not know, and have you not seen, this done before?

Question to you and THEM, the New Journal, "Integrative Psychological and Behavioral Science" -- do you not know, and have you not seen, this done before? There appears to be a core problem for...

02 March 2021 3,024 2 View

Is it necessary to report effect size (ES) in statistics of biomedical research given that we already report p values routinely?

Pls share your thoughts

01 March 2021 7,330 4 View

Which reagent is best among 'Dimethylglyoxime" and "Dithiothreitol" for spectroscopic determination of Nickel ?

What I think is Dithiothreitol. As it is water-soluble and does not form a precipitate. But, the thing is it contains sulphur which is quite hazardous to aquatic animals.

01 March 2021 8,374 4 View

How to include original NMR data in a manuscript?

hello. i am junior researcher. I received a comment from a reviewer that he could not find NMR data in my submitted paper. I had included the NMR graph with explanation and formula to calculate...

27 February 2021 734 4 View

Uncertianiny in using dry or wet basis in mixing a sediment with fuel oil?

Hello I'm currently working on a topic related to studying the anaerobic biodegradation of TPH in marine sediments. In this work, sediment should be mixed with fuel oil to a concentration of 20 g...

24 February 2021 9,839 3 View

How to identify what type of fillers are in a polymer?

Hello everyone, I have some PHAs blended with fillers and nucleating agents, yet I don't know what kind of fillers or nucleating agents. The producer has shut down and there's no way to get in...

24 February 2021 1,356 8 View

Is it mandatory to specify Subjects Combinations in Generalized Linear Mixed Models (SPSS)?

Hi all, I have data with two levels: lets think of the classic example of students and schools. When running the analysis in SPSS and selecting the Random Effects, we can select (we can or we...

24 February 2021 7,379 4 View

Do you think there is cognitive oversaturation in the current pandemic? What impact can this have? And other manifestations?

Dear colleagues, Do you think there is cognitive oversaturation in the current pandemic? What impact can this have? And other manifestations? The question is mainly aimed at adolescents (pupils,...

23 February 2021 7,796 4 View