Amikacin is a polar drug meant for parenteral use against gm negative bacteria.In some cases,different forms of amikacin meant for local application are used but can injection amikacin is effective if applied directly on wounds?
Hello, in my opinion and my knowledge, using injectable antibiotics locally on wounds leads to bacterial resistance. Silver Sulfadiazin was and stills the best local antibacterial topic for wounds and burns, it is effective on most germs and yeasts.
I think that use of antibiotics locali on wound is not good and has no effect on bacterial burden. The local use may also lead to bacterial resistance or even to alergy on this antibiotic.